{"id":28101,"date":"2025-10-11T17:12:01","date_gmt":"2025-10-11T09:12:01","guid":{"rendered":"http:\/\/cxounion.cn\/?p=28101"},"modified":"2025-10-11T17:12:05","modified_gmt":"2025-10-11T09:12:05","slug":"%e9%99%86%e9%81%93%e5%9f%b9%e5%8c%bb%e9%99%a2%e8%a1%80%e6%b6%b2%e7%a7%91%e5%bc%a0%e5%bc%a6%e4%b8%bb%e4%bb%bb%e5%9c%a8blood-advances%e5%8f%91%e8%a1%a8bcma-car-t%e7%bb%86%e8%83%9e%e7%96%97%e6%b3%95","status":"publish","type":"post","link":"http:\/\/cxounion.cn\/index.php\/2025\/10\/11\/%e9%99%86%e9%81%93%e5%9f%b9%e5%8c%bb%e9%99%a2%e8%a1%80%e6%b6%b2%e7%a7%91%e5%bc%a0%e5%bc%a6%e4%b8%bb%e4%bb%bb%e5%9c%a8blood-advances%e5%8f%91%e8%a1%a8bcma-car-t%e7%bb%86%e8%83%9e%e7%96%97%e6%b3%95\/","title":{"rendered":"\u9646\u9053\u57f9\u533b\u9662\u8840\u6db2\u79d1\u5f20\u5f26\u4e3b\u4efb\u5728Blood Advances\u53d1\u8868BCMA CAR-T\u7ec6\u80de\u7597\u6cd5\u6700\u65b0\u4e34\u5e8a\u7814\u7a76\u6210\u679c"},"content":{"rendered":"\n<p>\u5317\u4eac2025\u5e7410\u67089\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u8fd1\u65e5\uff0c\u56fd\u9645\u8840\u6db2\u5b66\u671f\u520a<em><strong>Blood Advances<\/strong><\/em>\u6742\u5fd7\u53d1\u8868\u4e86\u9646\u9053\u57f9\u533b\u5b66\u56e2\u961f\u4e00\u9879\u524d\u77bb\u6027\u4e34\u5e8a\u7814\u7a76\uff0c<strong>\u5f20\u5f26\u4e3b\u4efb\u4e3a\u7b2c\u4e00\u4f5c\u8005\uff0c\u9646\u4f69\u534e\u9662\u957f\u4e3a\u901a\u8baf\u4f5c\u8005<\/strong>\uff0c\u9898\u4e3a\u300aEfficacy and safety of BCMA nanobody CAR T-cell therapy in relapsed or refractory plasma cell myeloma\u300b\uff08BCMA\u7eb3\u7c73\u6297\u4f53CAR-T\u7ec6\u80de\u7597\u6cd5\u5728\u590d\u53d1\/\u96be\u6cbb\u6027\u6d46\u7ec6\u80de\u6027\u9aa8\u9ad3\u7624\u4e2d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff09\uff0c\u62a5\u9053\u4e86\u5e94\u7528\u7eb3\u7c73\u4f53\u7684BCMA CAR-T\u7ec6\u80de\u6cbb\u7597\u591a\u7ebf\u6cbb\u7597\u540e\u96be\u6cbb\u590d\u53d1\u7684\u6d46\u7ec6\u80de\u80bf\u7624\u7684\u7a81\u7834\u6027\u4e34\u5e8a\u7814\u7a76\u6210\u679c\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"599\" height=\"364\" src=\"http:\/\/cxounion.cn\/wp-content\/uploads\/2025\/10\/image_844202_22982292.jpg\" alt=\"\" class=\"wp-image-28102\" srcset=\"http:\/\/cxounion.cn\/wp-content\/uploads\/2025\/10\/image_844202_22982292.jpg 599w, http:\/\/cxounion.cn\/wp-content\/uploads\/2025\/10\/image_844202_22982292-300x182.jpg 300w\" sizes=\"(max-width: 599px) 100vw, 599px\" \/><\/figure>\n\n\n\n<p class=\"has-text-align-center\"><strong>\u7814\u7a76\u80cc\u666f<\/strong><\/p>\n\n\n\n<p>\u590d\u53d1\/\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08R\/R 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CAR-T\u7ec6\u80de\u9759\u8109\u56de\u8f93\u3002\u4e3b\u8981\u7ec8\u70b9\u4e3a\u603b\u7f13\u89e3\u7387\uff08ORR\uff09\u53ca\u5b89\u5168\u6027\uff0c\u6b21\u8981\u7ec8\u70b9\u5305\u62ec\u7f13\u89e3\u6df1\u5ea6\u3001\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DOR\uff09\u3001\u65e0\u8fdb\u5c55\u751f\u5b58\uff08PFS\uff09\u3001\u603b\u751f\u5b58\uff08OS\uff09\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong>\u7814\u7a76\u7ed3\u679c<\/strong><\/p>\n\n\n\n<p>\u7ed3\u679c\u663e\u793a\uff0cBCMA CAR-T\u7ec6\u80de\u8f93\u6ce8\u540e3\u4e2a\u6708\u7684\u603b\u4f53\u7f13\u89e3\u7387\uff08ORR\uff09\u8fbe\u5230100%\uff0c\u6df1\u5ea6\u7f13\u89e3\u7387\uff08CR+VGPR\uff0981.5%\uff0c\u4e2d\u4f4d\u7f13\u89e3(DOR)\u6301\u7eed\u65f6\u95f411\u4e2a\u6708\uff082-36\u4e2a\u6708\uff09\u3002\u9ad8\u5371\u9057\u4f20\u5b66\u60a3\u80053\u4e2a\u6708CR\u738772.7%\uff0c1\u5e74PFS 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CAR-T\u7684\u663e\u8457\u4f18\u52bf\uff0c\u4e3a\u5236\u5b9a\u66f4\u4e3a\u7cbe\u51c6\u7684\u4e34\u5e8a\u6cbb\u7597\u65b9\u6848\u63d0\u4f9b\u4e86\u6709\u529b\u652f\u6301\u3002<\/p>\n\n\n\n<p>\u672a\u6765\uff0c\u9646\u9053\u57f9\u533b\u9662\u5c06\u6301\u7eed\u6df1\u8015CAR-T\u7ec6\u80de\u6cbb\u7597\u9886\u57df\uff0c\u6df1\u5165\u63a2\u7d22\u5176\u4e0e\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u3001\u6297\u4f53\u836f\u7269\u53ca\u5c0f\u5206\u5b50\u9776\u5411\u836f\u7269\u7684\u8054\u5408\u6cbb\u7597\u7b56\u7565\uff0c\u81f4\u529b\u4e8e\u63a8\u8fdb\u4e2a\u4f53\u5316\u3001\u7cbe\u51c6\u5316\u7684\u6cbb\u7597\u8def\u5f84\uff0c\u60e0\u53ca\u66f4\u591a\u56fd\u5185\u5916\u60a3\u8005\uff0c\u5207\u5b9e\u63d0\u5347\u5176\u751f\u5b58\u8d28\u91cf\u4e0e\u957f\u671f\u9884\u540e\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter\"><a href=\"https:\/\/mma.prnasia.com\/media2\/2792304\/image_844202_22982323.jpg?p=publish\" target=\"_blank\" rel=\"noreferrer noopener\"><img decoding=\"async\" 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href=\"http:\/\/cxounion.cn\">http:\/\/www.cxounion.cn\/<\/a>)\u5185\u5bb9\u4e3b\u8981\u6765\u81ea\u539f\u521b\u3001\u5408\u4f5c\u5a92\u4f53\u4f9b\u7a3f\u548c\u7b2c\u4e09\u65b9\u6295\u7a3f\uff0c\u51e1\u5728\u672c\u7f51\u7ad9\u51fa\u73b0\u7684\u4fe1\u606f\uff0c\u5747\u4ec5\u4f9b\u53c2\u8003\u3002\u672c\u7f51\u7ad9\u5c06\u5c3d\u529b\u786e\u4fdd\u6240\u63d0\u4f9b\u4fe1\u606f\u7684\u51c6\u786e\u6027\u53ca\u53ef\u9760\u6027\uff0c\u4f46\u4e0d\u4fdd\u8bc1\u6709\u5173\u8d44\u6599\u7684\u51c6\u786e\u6027\u53ca\u53ef\u9760\u6027\uff0c\u8bfb\u8005\u5728\u4f7f\u7528\u524d\u8bf7\u8fdb\u4e00\u6b65\u6838\u5b9e\uff0c\u5e76\u5bf9\u4efb\u4f55\u81ea\u4e3b\u51b3\u5b9a\u7684\u884c\u4e3a\u8d1f\u8d23\u3002\u672c\u7f51\u7ad9\u5bf9\u6709\u5173\u8d44\u6599\u6240\u5f15\u81f4\u7684\u9519\u8bef\u3001\u4e0d\u786e\u6216\u9057\u6f0f\uff0c\u6982\u4e0d\u8d1f\u4efb\u4f55\u6cd5\u5f8b\u8d23\u4efb\u3002<\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color\" 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