{"id":31285,"date":"2025-11-05T17:09:37","date_gmt":"2025-11-05T09:09:37","guid":{"rendered":"http:\/\/cxounion.cn\/?p=31285"},"modified":"2025-11-05T17:09:37","modified_gmt":"2025-11-05T09:09:37","slug":"%e9%99%86%e9%81%93%e5%9f%b9%e5%8c%bb%e9%99%a2%e8%a1%80%e6%b6%b2%e7%a7%91%e5%bc%a0%e5%bc%a6%e4%b8%bb%e4%bb%bb%e5%9c%a8%e8%8b%b1%e5%9b%bd%e8%a1%80%e6%b6%b2%e5%ad%a6%e6%9d%82%e5%bf%97bjhaem%e4%b8%8a","status":"publish","type":"post","link":"http:\/\/cxounion.cn\/index.php\/2025\/11\/05\/%e9%99%86%e9%81%93%e5%9f%b9%e5%8c%bb%e9%99%a2%e8%a1%80%e6%b6%b2%e7%a7%91%e5%bc%a0%e5%bc%a6%e4%b8%bb%e4%bb%bb%e5%9c%a8%e8%8b%b1%e5%9b%bd%e8%a1%80%e6%b6%b2%e5%ad%a6%e6%9d%82%e5%bf%97bjhaem%e4%b8%8a\/","title":{"rendered":"\u9646\u9053\u57f9\u533b\u9662\u8840\u6db2\u79d1\u5f20\u5f26\u4e3b\u4efb\u5728\u82f1\u56fd\u8840\u6db2\u5b66\u6742\u5fd7BJHaem\u4e0a\u53d1\u8868CD7 CAR-T\u540e\u514d\u75ab\u91cd\u5efa\u6700\u65b0\u7814\u7a76\u6210\u679c"},"content":{"rendered":"\n<p>\u5317\u4eac2025\u5e7410\u670831\u65e5&nbsp;\/\u7f8e\u901a\u793e\/ &#8212; \u8fd1\u65e5\uff0c\u9646\u9053\u57f9\u533b\u9662\u8840\u6db2\u79d1\u5f20\u5f26\u4e3b\u4efb\u4e00\u9879\u5173\u4e8eCD7 CAR-T\u540e\u514d\u75ab\u91cd\u5efa\u7684\u6700\u65b0\u4e34\u5e8a\u7814\u7a76\u6210\u679c\u2014&#8221;Immune reconstitution after CD7 CAR-T cell therapy for refractory\/relapsed acute T-lymphoblastic leukaemia\/lymphoblastic lymphoma (R\/R T-ALL\/LBL)&#8221;\u53d1\u8868\u4e8e\u56fd\u9645\u77e5\u540d\u8840\u6db2\u5b66\u671f\u520a\u300aBritish Journal of Haematology\u300b(\u82f1\u56fd\u8840\u6db2\u5b66\u6742\u5fd7)\u3002\u8be5\u7814\u7a76\u7cfb\u7edf\u8bc4\u4f30\u4e86\u590d\u53d1\/\u96be\u6cbb\u6027T\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u6dcb\u5df4\u7624\uff08R\/R T-ALL\/LBL\uff09\u60a3\u8005\u5728\u63a5\u53d7CD7 CAR-T\u7ec6\u80de\u6cbb\u7597\u540e\u7684\u4e09\u4e2a\u6708\u5185\u7684\u514d\u75ab\u91cd\u5efa\u7279\u5f81\uff0c\u4e3a\u5168\u7403\u5e7f\u6cdb\u5173\u6ce8\u7684CD7 CAR-T\u540e\u514d\u75ab\u7f3a\u9677\u98ce\u9669\u95ee\u9898\u63d0\u4f9b\u4e86\u91cd\u8981\u4e34\u5e8a\u8bc1\u636e\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"599\" height=\"316\" src=\"http:\/\/cxounion.cn\/wp-content\/uploads\/2025\/11\/image-1.jpeg\" alt=\"\" class=\"wp-image-31290\" title=\"\" srcset=\"http:\/\/cxounion.cn\/wp-content\/uploads\/2025\/11\/image-1.jpeg 599w, http:\/\/cxounion.cn\/wp-content\/uploads\/2025\/11\/image-1-300x158.jpeg 300w\" sizes=\"(max-width: 599px) 100vw, 599px\" \/><\/figure>\n\n\n\n<p><strong>\u7814\u7a76\u80cc\u666f<\/strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-body-text-color\">\u6570\u5b57\u5316\u8f6c\u578bwww.szhzxw,cn<\/mark><\/p>\n\n\n\n<p>CD7 CAR-T\u7ec6\u80de\u6cbb\u7597\u5728\u590d\u53d1\/\u96be\u6cbb\u6027\uff08R\/R\uff09\u6025\u6027T\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u6dcb\u5df4\u7624\uff08T-ALL\/LBL\uff09\u4e2d\u53d6\u5f97\u4e86\u4ee4\u4eba\u77a9\u76ee\u7684\u7597\u6548\uff0c\u4f46\u7531\u4e8e\u5176\u9776\u5411T\u7ec6\u80de\u6297\u539fCD7\uff0c\u5728CART\u540e\u662f\u5426\u4f1a\u5f15\u8d77T\u7ec6\u80de\u7684\u7f3a\u5931\u800c\u5bfc\u81f4\u7684\u4e25\u91cd\u514d\u75ab\u7f3a\u9677\uff0c\u59cb\u7ec8\u4ee4\u4eba\u62c5\u5fe7\u3002\u800c\u8fc4\u4eca\u4e3a\u6b62\uff0c\u6ca1\u6709\u660e\u786e\u4e34\u5e8a\u6570\u636e\u7684\u7ed9\u4ee5\u76f8\u5173\u89e3\u8bfb\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u65b9\u6cd5<\/strong><\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u6bd4\u8f83\u4e8660\u4f8b\u63a5\u53d7CD7 CAR-T\uff08NS7CAR-T\uff09\u6cbb\u7597\u7684R\/R T-ALL\/LBL\u60a3\u8005\u4e0e60\u4f8b\u63a5\u53d7CD19 CAR-T\u6cbb\u7597\u7684R\/R B-ALL\u60a3\u8005\uff0cCAR-T\u6cbb\u7597\u540e\u77ed\u671f\u7684\u611f\u67d3\u53d1\u751f\u7387\u53ca\u514d\u75ab\u7ec6\u80de\u4e9a\u7fa4\u53d8\u5316\u3002\u89c2\u5bdf\u65f6\u95f4\u4e3a\u81eaCART\u7ec6\u80de\u8f93\u6ce8\u8d77\uff0c\u76f4\u81f3\u8fdb\u884c\u540c\u79cd\u5f02\u57fa\u56e0\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\uff08HSCT\uff09\u6216\u6700\u957f\u968f\u8bbf3\u4e2a\u6708\u3002<\/p>\n\n\n\n<p><strong>\u7814\u7a76\u7ed3\u679c<\/strong><\/p>\n\n\n\n<p>\u7ed3\u679c\u663e\u793a\uff0c\u4e24\u7ec4\u603b\u4f53\u611f\u67d3\u7387\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff0836.67% vs. 24.56%\uff0cp=0.24\uff09\uff0c\u4f46CD7 CAR-T\u7ec4\u65e9\u671f\u514d\u75ab\u6548\u5e94\u7ec6\u80de\u76f8\u5173\u8840\u6db2\u6bd2\u6027\uff08ICAHT\uff09\u2162\u2013\u2163\u7ea7\u53d1\u751f\u7387\u663e\u8457\u9ad8\u4e8eCD19 CAR-T\u7ec4\uff0833.9% vs. 16.7%\uff0cp=0.03\uff09\u3002\u8f93\u6ce8\u540e\u5206\u6790\u53d1\u73b0\uff0cCD7(+) T\u7ec6\u80de\u660e\u663e\u51cf\u5c11\uff0c\u800c\u975eCAR-T\u6765\u6e90\u7684CD7(-) T\u7ec6\u80de\u663e\u8457\u4e0a\u5347\uff0c\u5176\u6bd4\u4f8b\u5728\u7b2c28\u5929\u4e2d\u4f4d\u503c\u8fbe84.4%\uff08\u8303\u56f4\uff1a22.1%-99.9%\uff09\u3002\u540c\u65f6\uff0c\u968f\u7740CD7(+) NK\u7ec6\u80de\u7684\u6e05\u9664\uff0cCD7(-) NK\u7ec6\u80de\u51e0\u4e4e\u5b8c\u5168\u5360\u636e\u4e3b\u5bfc\u5730\u4f4d\u3002<\/p>\n\n\n\n<p><strong>\u7ed3\u8bba<\/strong><\/p>\n\n\n\n<p>\u7814\u7a76\u8868\u660e\uff0cCD7 CAR-T\u6cbb\u7597\u867d\u7136\u6e05\u9664\u4e86CD7(+) T\u7ec6\u80de\uff0c\u4f46\u5e76\u672a\u5bfc\u81f4\u77ed\u671f\u611f\u67d3\u7387\u5347\u9ad8\u3002\u975eCAR-T\u6765\u6e90\u7684CD7(-) T\u7ec6\u80de\u548cNK\u7ec6\u80de\u53ef\u4ee5\u8fc5\u901f\u6269\u589e\u4e0e\u8865\u4f4d\uff0c\u7ef4\u6301\u514d\u75ab\u7cfb\u7edf\u5e73\u8861\u3002\u8fd9\u4e00\u7ed3\u679c\u63d0\u793a\uff0cCD7 CAR-T\u4e0eCD19 CAR-T\u56e0\u4f5c\u7528\u9776\u70b9\u6240\u5c5e\u8c31\u7cfb\u4e0d\u540c\u800c\u5448\u73b0\u51fa\u72ec\u7279\u7684\u514d\u75ab\u91cd\u5efa\u673a\u5236\u3002<\/p>\n\n\n\n<p>\u4f5c\u4e3a\u56fd\u9645\u516c\u8ba4\u7684T\u7ec6\u80de\u6076\u6027\u80bf\u7624\u6cbb\u7597\u524d\u6cbf\u9886\u57df\uff0cCD7 CAR-T\u7597\u6cd5\u957f\u671f\u9762\u4e34&#8221;\u6709\u6548\u4f46\u514d\u75ab\u7f3a\u9677\u98ce\u9669\u8f83\u9ad8&#8221;\u7684\u4e34\u5e8a\u987e\u8651\uff0c\u8fd9\u9879\u7814\u7a76\u4e3a\u5168\u7403\u540c\u884c\u63d0\u4f9b\u4e86\u5927\u6837\u672c\u3001\u7cfb\u7edf\u6027\u7684CD7 CAR-T\u514d\u75ab\u91cd\u5efa\u5206\u6790\u6570\u636e\uff0c\u4e3aT\u7cfb\u767d\u8840\u75c5\/\u6dcb\u5df4\u7624\u7684\u7cbe\u51c6\u6cbb\u7597\u548c\u514d\u75ab\u7ba1\u7406\u63d0\u4f9b\u4e86\u575a\u5b9e\u7684\u79d1\u5b66\u4f9d\u636e\uff0c\u5bf9\u5236\u5b9aCD7 CAR-T\u6cbb\u7597\u540e\u7684\u7efc\u5408\u7ba1\u7406\u7b56\u7565\uff08\u5305\u62ec\u611f\u67d3\u9632\u63a7\u3001\u514d\u75ab\u76d1\u6d4b\u548c\u79fb\u690d\u65f6\u673a\uff09\u5177\u6709\u73b0\u5b9e\u6307\u5bfc\u610f\u4e49\u3002\u540c\u65f6\uff0c\u4e5f\u6807\u5fd7\u7740\u9646\u9053\u57f9\u533b\u5b66\u56e2\u961f\u5728T\u7ec6\u80de\u6076\u6027\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u9886\u57df\u7684\u6301\u7eed\u5f15\u9886\u4e0e\u521b\u65b0\u5b9e\u8df5\u3002<\/p>\n\n\n\n<p>\u672a\u6765\uff0c\u9646\u9053\u57f9\u533b\u9662\u5c06\u6301\u7eed\u6df1\u8015CAR-T\u7ec6\u80de\u6cbb\u7597\u9886\u57df\uff0c\u6df1\u5165\u63a2\u7d22\u5176\u4e0e\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u3001\u6297\u4f53\u836f\u7269\u53ca\u5c0f\u5206\u5b50\u9776\u5411\u836f\u7269\u7684\u8054\u5408\u6cbb\u7597\u7b56\u7565\uff0c\u81f4\u529b\u4e8e\u63a8\u8fdb\u4e2a\u4f53\u5316\u3001\u7cbe\u51c6\u5316\u7684\u6cbb\u7597\u8def\u5f84\uff0c\u60e0\u53ca\u66f4\u591a\u56fd\u5185\u5916\u60a3\u8005\uff0c\u5207\u5b9e\u63d0\u5347\u5176\u751f\u5b58\u8d28\u91cf\u4e0e\u957f\u671f\u9884\u540e\u3002<\/p>\n\n\n\n<p><strong>\u4f5c\u8005\u7b80\u4ecb<\/strong><\/p>\n\n\n\n<p><a href=\"https:\/\/mma.prnasia.com\/media2\/2809943\/image_844202_4043083.jpg?p=publish\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><br>\u5f20\u5f26 \u9646\u9053\u57f9\u533b\u9662\u8840\u6db2\u79d1\u4e3b\u4efb<\/p>\n\n\n\n<p>\u4e3b\u4efb\u533b\u5e08\uff0c\u8840\u6db2\u5b66\u535a\u58eb\u3002\u64c5\u957f\u5404\u79cd\u826f\u6027\u6076\u6027\u8840\u6db2\u75c5\u7684MICM\uff08\u5f62\u6001\u3001\u514d\u75ab\u5206\u578b\u3001\u67d3\u8272\u4f53\u3001\u878d\u5408\u57fa\u56e0\u3001\u57fa\u56e0\u7a81\u53d8\uff09\u7efc\u5408\u8bca\u65ad\uff0c\u5e76\u6839\u636e\u76f8\u5e94\u7ed3\u679c\u8fdb\u884c\u5371\u9669\u5ea6\u5206\u5c42\u5206\u5c42\uff0c\u7ed9\u4ee5\u76f8\u5e94\u4e2a\u4f53\u5316\u6cbb\u7597\u3002\u64c5\u957f\u6076\u6027\u8840\u6db2\u75c5\u6cbb\u7597\uff0c\u7279\u522b\u662f\u5404\u578b\u767d\u8840\u75c5\u3001\u6dcb\u5df4\u7624\u3001\u9aa8\u9ad3\u7624\u7684\u5316\u7597\u3001\u9776\u5411\u6cbb\u7597\u548cCAR-T\u6cbb\u7597\u3002\u5728\u590d\u53d1\/\u96be\u6cbb\u6076\u6027\u8840\u6db2\u75c5\u65b9\u9762\u79ef\u7d2f\u5927\u91cf\u7ecf\u9a8c\uff0c\u53c2\u8003\u56fd\u9645\u6700\u65b0\u836f\u7269\u548c\u514d\u75ab\u7597\u6cd5\uff0c\u4e3a\u60a3\u8005\u5236\u5b9a\u4e2a\u4f53\u5316\u6cbb\u7597\u65b9\u6848\u3002\u64c5\u957f\u6025\u6027\u65e9\u5e7c\u7c92\u7ec6\u80de\u767d\u8840\u75c5\u7684\u6cbb\u7597\uff0c\u65e0\u8bba\u662f\u521d\u6cbb\u8fd8\u662f\u590d\u53d1\u5747\u6709\u5927\u91cf\u6210\u529f\u7ecf\u9a8c\u5e76\u53d1\u8868\u76f8\u5173\u6587\u7ae0\u3002\u64c5\u957f\u81ea\u4f53\u79fb\u690d\u6cbb\u7597\u6dcb\u5df4\u7624\u3001\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center has-cyan-bluish-gray-color has-text-color has-extra-small-font-size\">\u7531<a href=\"http:\/\/cxounion.cn\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/a>\u8f6c\u8f7d\u800c\u6210\uff0c\u6765\u6e90\u4e8e\u9646\u9053\u57f9\u533b\u7597\u96c6\u56e2\uff1b\u7f16\u8f91\/\u7ffb\u8bd1\uff1aCXO UNIONCXO\u8054\u76df\u5c0fU\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size\">\u5982\u9700\u52a0\u5165<a href=\"http:\/\/weixin.qq.com\/r\/fxJxaVHE1AyrrRUK90dt\">CXO UNION\uff08CXO\u8054\u76df\uff09<\/a>\u9ad8\u7ba1\u793e\u7fa4\uff0c\u8bf7\u8054\u7cfb\u793e\u7fa4\u5c0f\u4f19\u4f34\u54e6~<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img decoding=\"async\" src=\"http:\/\/cxounion.cn\/wp-content\/uploads\/2023\/06\/CXOUNION\u65b0\u4e8c\u7ef4\u7801.png\" alt=\"\"\/><\/figure>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color\" style=\"font-size:14px\">\u514d\u8d23\u58f0\u660e: \u672c\u7f51\u7ad9(<a href=\"http:\/\/cxounion.cn\">http:\/\/www.cxounio<\/a><em><a href=\"http:\/\/cxounion.cn\">n.cn\/<\/a>)\u5185\u5bb9\u4e3b\u8981\u6765\u81ea\u539f\u521b\u3001\u5408\u4f5c\u5a92\u4f53\u4f9b\u7a3f\u548c\u7b2c\u4e09\u65b9\u6295\u7a3f\uff0c\u51e1\u5728\u672c\u7f51\u7ad9\u51fa\u73b0\u7684\u4fe1\u606f\uff0c\u5747\u4ec5\u4f9b\u53c2\u8003\u3002\u672c\u7f51\u7ad9\u5c06\u5c3d\u529b\u786e\u4fdd\u6240\u63d0\u4f9b\u4fe1\u606f\u7684\u51c6\u786e\u6027\u53ca\u53ef\u9760\u6027\uff0c\u4f46\u4e0d\u4fdd\u8bc1\u6709\u5173\u8d44\u6599\u7684\u51c6\u786e\u6027\u53ca\u53ef\u9760\u6027\uff0c\u8bfb\u8005\u5728\u4f7f\u7528\u524d\u8bf7\u8fdb\u4e00\u6b65\u6838\u5b9e\uff0c\u5e76\u5bf9\u4efb\u4f55\u81ea\u4e3b\u51b3\u5b9a\u7684\u884c\u4e3a\u8d1f\u8d23<\/em>\u3002\u672c\u7f51\u7ad9\u5bf9\u6709\u5173\u8d44\u6599\u6240\u5f15\u81f4\u7684\u9519\u8bef\u3001\u4e0d\u786e\u6216\u9057\u6f0f\uff0c\u6982\u4e0d\u8d1f\u4efb\u4f55\u6cd5\u5f8b\u8d23\u4efb\u3002<\/p>\n\n\n\n<p class=\"has-cyan-bluish-gray-color has-text-color\" style=\"font-size:14px\">\u672c\u7f51\u7ad9\u520a\u8f7d\u7684\u6240\u6709\u5185\u5bb9(\u5305\u62ec\u4f46\u4e0d\u4ec5\u9650\u6587\u5b57\u3001\u56fe\u7247\u3001LOG<\/p>\n","protected":false},"excerpt":{"rendered":"<p> [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":31290,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[860,1],"tags":[1257,1020],"class_list":["post-31285","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-860","category-other-news","tag-bob","tag-1020"],"_links":{"self":[{"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/posts\/31285","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/comments?post=31285"}],"version-history":[{"count":1,"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/posts\/31285\/revisions"}],"predecessor-version":[{"id":31291,"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/posts\/31285\/revisions\/31291"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/media\/31290"}],"wp:attachment":[{"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/media?parent=31285"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/categories?post=31285"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/cxounion.cn\/index.php\/wp-json\/wp\/v2\/tags?post=31285"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}