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class=\"has-text-align-center\">\u5982\u9700\u52a0\u5165CXO UNION\uff08CXO\u8054\u76df\uff09\u9ad8\u7ba1\u793e\u7fa4\uff0c\u8bf7\u8054\u7cfb\u793e\u7fa4\u5c0f\u4f19\u4f34\u54e6~<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"http:\/\/cxounion.cn\/wp-content\/uploads\/2023\/04\/cxo\u7ed3\u5c3e\u4e8c\u7ef4\u7801.png\" alt=\"\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u7ffb\u8bd1<\/h2>\n\n\n\n<p>&#8220;Even though we have good clinical technology, a lot of good doctors. And a lot of innovative drugs, the public awareness of early screening is still low.&#8221; <\/p>\n\n\n\n<p>During the 29th National Cancer Prevention and Control Awareness Week, April 15-21, Zhu Yeqing, chairman and CEO of Nuhui Health, delivered a keynote speech at the &#8220;Comprehensive Action on Cancer Prevention. And Control &#8212; 21CC 2023 Live Broadcast of the National Cancer Prevention and Control Publicity Week&#8221;. Which was launched by the 21st Century Economic Herald under the Southern Finance Omnimedia Group and the 21st Century New Health Research Institute. And said that the key to cancer prevention and control lies in the change of cognition.<\/p>\n\n\n\n<p>Zhu Yeqing points out that most people still have a very low awareness of screening when they are asymptomatic. However, the COVID-19 pandemic has helped educate the market. More and more people believe that recognizing a major disease like cancer. That moving the threshold forward and sinking the center of gravity, is a very important step in health management. More and more people realize that asymptomatic screening is the most effective way to really prevent these major diseases.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">improve the quality of life<\/h4>\n\n\n\n<p>Zhu Yeqing pointed out that currently there is a four-tier cancer prevention and control system. And the first-tier prevention and control system is to avoid cancer as much as possible. The secondary prevention and control system is to detect cancer in the early stage of development and nip it in the bud; Tertiary prevention and control means early detection and intervention by advanced means; Level 4 prevention and control is to improve the quality of life of patients through effective treatment. &#8220;The golden window for cancer prevention is actually in the screening stage, the secondary and tertiary defense stage. And we hope that when the disease does not develop into cancer, through screening. We can detect it early and intervene early so that we can reduce the incidence of cancer.&#8221;<\/p>\n\n\n\n<p>It is worth noting that Zhu Yeqing also mentioned that some traditional screening methods will bring strong discomfort to patients. And there are certain blind areas in the screening field. &#8220;Take intestinal screening for example. According to our statistics, in 95% of physical examinations, intestinal screening is a blind area. Which means that we lack effective measures to manage and maintain our intestinal health. And, although painless colonoscopes are available, the average waiting time is six months to a year, so there is an urgent need for simple, painless early screening products.&#8221;<\/p>\n\n\n\n<p>Zhu Yeqing further pointed out that in the medical system, resources for colonoscopy are also in short supply. Not only the equipment, but also the medical staff who can do colonoscopy are also in serious shortage in China, and the supply is far from sufficient. As for the current situation of tumor screening, some better means and more advanced technology are needed to help and replace the vacancy, so as to face the realistic challenges of tumor screening.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Cancer screening in Chinese digestive System &#8216;missing&#8217;<\/h3>\n\n\n\n<p>Digestive system cancers account for four of the top six most common cancers in China. &#8220;This fully confirms what we often hear, that Chinese people eat a lot of their diseases.&#8221; Zhu Yeqing said.<\/p>\n\n\n\n<p>Among cancers of the digestive tract, bowel cancer and stomach cancer are particularly prominent. In the newly released National Cancer Atlas, bowel cancer has become the second most frequent cancer in China, and Chinese patients account for 30% of the new cancer patients in the world. Gastric cancer is the third most frequent cancer in China, accounting for 44% of the new cancer patients in the world.<\/p>\n\n\n\n<p>This fully shows that digestive system cancer is a very important factor troubling the health of Chinese people. But there is currently a lack of effective screening for many cancers. For example, there is a high incidence of bowel cancer in China, which lacks effective screening methods. At present in the routine physical examination of our country, the only relevant screening is stool occult blood test. Statistically, intestinal screening is a blind spot in 95 percent of physical examinations.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">&#8220;The colonoscopy is so painful that it feels like the doctor is beating the stomach with an iron stick full of thorns. I don&#8217;t want to do it again<\/h4>\n\n\n\n<p>One of the main reasons for this is that patients are more uncomfortable with traditional screening methods. For example, one patient said, &#8220;The colonoscopy is so painful that it feels like the doctor is beating the stomach with an iron stick full of thorns. I don&#8217;t want to do it again.&#8221;<\/p>\n\n\n\n<p>In fact, colonoscopy resources are in short supply in the current health care system. Colonoscopy resources here are not only common testing equipment, but more importantly, medical personnel related to colonoscopy. In China, there is a serious shortage and the supply is far from sufficient. Hardware can be solved in a variety of ways, but without a doctor, no matter how many scenarios you have, you can&#8217;t really use the user effectively.<\/p>\n\n\n\n<p>&#8220;If all the current colonoscopy resources in China were used for screening, it would take more than 56 years to complete one colonoscopy for the screening population, which is a very serious fact. So we need better technology to fill the gap in cancer screening.&#8221; Zhu Yeqing said.<\/p>\n\n\n\n<p>What screening is clinically valuable? According to Zhu Yeqing, three points are important. First, screening needs to have clear clinical guiding significance. For example, when a doctor learns the results of a screening test, he or she knows exactly what to do next.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">worry about the risk of missing a test<\/h4>\n\n\n\n<p>For bowel cancer, for example, if the screening result is positive, the doctor should have the relevant data to decide whether the patient should proceed to the next colonoscopy program. More importantly, if the screening results are negative, doctors will not have to worry about the risk of missing a test, allowing users to avoid using limited resources for colonoscopy screening at this stage when they are asymptomatic.<\/p>\n\n\n\n<p>The second is a simple diagnosis method. &#8220;When a user is known to be positive through screening, the next step for doctors is to use the gold standard to determine whether the user has cancer or is in a precancerous stage. There needs to be some simple diagnostic method to help doctors determine that.&#8221; Zhu Yeqing said.<\/p>\n\n\n\n<p>For example, bowel cancer and stomach cancer can be judged by endoscopy or even biopsy, and may be invasive or even require surgery. Many cancers, especially solid cancers, lack an easy way to diagnose them, so screening will be difficult.<\/p>\n\n\n\n<p>And the third is a viable clinical intervention, which is also a very important point. &#8220;When a patient is diagnosed with cancer, it is important that there are effective interventions available clinically. Without interventions, even if they are detected, they will not improve, and they will increase anxiety.&#8221;<\/p>\n\n\n\n<p>To sum up, a good screening method must have clear clinical guidance, simple diagnosis method and feasible clinical intervention means.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Screening scene subsidence is the future direction<\/h3>\n\n\n\n<p>Setting the screening scenario as close to home as possible can greatly improve screening effectiveness and compliance in high-risk populations.<\/p>\n\n\n\n<p>Zhu Yeqing also stressed on more than one public occasion that the application scene of early screening products must be outside hospitals. Meanwhile, Nuohui should clarify the clinical path of early screening products, so that the products have more clear clinical significance, so that more professional doctors can endorse the products, which is also the key for Nuohui to serve ordinary consumers based on the hospital.<\/p>\n\n\n\n<p>Take Nuohui Health product Chang Weiqing as an example, its use method is simple, sample 5 grams of stool at home, and then send to our testing center, the test report can be produced in 3 to 5 working days. Test positive users need to go to the colonoscopy for further diagnosis, negative users can rest assured to go home.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">It is worth noting that this product is currently the only one approved by the State Food and Drug Administration of cancer early screening license. <\/h4>\n\n\n\n<p>In 2020, the official website of NMPA shows that it has approved the registration of Novi Health&#8217;s innovative product &#8220;KRAS gene mutation and BMP3\/NDRG4 gene methylation and fecal occultic blood test kit (PCR fluorescence probe method &#8211; Colloidal gold method)&#8221;. This product is suitable for people aged 40-74 years old who are at high risk of colorectal cancer. It cannot replace colonoscopy, and the test results of this product should not be taken as the sole basis for clinical diagnosis.<\/p>\n\n\n\n<p>From 2021 to 2022, Nuohui Health has served more than 500,000 Chang Weiqing users to complete testing. The user base covers all 34 provincial-level administrative regions including Hong Kong, Macao and Taiwan. The report showed that the median age of the test subjects was 45 years old. The oldest age of colorectal cancer patients was 88 years old and the youngest age was 43 years old. The age of adenoma patients ranged from 85 years to 23 years. The highest positive rate was 11.2% in Shanghai, 10.8% in Guangdong and 9.1% in Beijing. <\/p>\n\n\n\n<h4 class=\"wp-block-heading\">is currently the only Helicobacter pylori detection product applicable to <\/h4>\n\n\n\n<p>Starting from the age of 40, the positive rate of patients aged 40-50 was 4.2%, that of those aged 50-60 was 5.8%. That of those aged 60-70 was 9.9%, and that of those over 70 was 10.9%. Based on colonoscopy, the disease data of Chang Weiqing positive and abnormal colonoscopy were as follows: adenoma and polyp accounted for 83.2%, colorectal cancer accounted for 2.7%, and abnormal other diseases accounted for 14.1%. Nuohui Health has been following a diversified commercial model based on serious medical treatment in hospitals. &#8220;Youyouguan&#8221; also extends the screening scene to families through self-testing by consumers. Youguan was approved as a Class III medical device registration certificate of the State Medical Products Administration on December 31, 2021. And is currently the only Helicobacter pylori detection product applicable to &#8220;consumer self-testing&#8221; in China.<\/p>\n\n\n\n<p>Helicobacter pylori was officially upgraded as a Class 1 carcinogen by the FDA in 2021, which is the most direct and important factor in causing gastric cancer.<\/p>\n\n\n\n<p>At present, the infection rate of Helicobacter pylori among Chinese people is very high. Studies show that more than 70 percent of Chinese families have at least one Helicobacter pylori positive patient. Youyouguan can fully realize home self-test. Users only need to take five sites on their stool samples, and the test report will be available within five minutes.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">make more people willing to participate in the screening<\/h4>\n\n\n\n<p>Different from the traditional expiratory method. Which requires the detection of hospitals or other professional institutions, Youyouguan can be detected at home with simple operation method, which can greatly reduce the threshold of screening, truly sink the focus of gastric cancer screening to the family, and make more people willing to participate in the screening.<\/p>\n\n\n\n<p>In addition, for products, the foundation of user trust is registered clinical data and compliance. Weiqing Chang, for example, underwent Clear-C, China&#8217;s first large-scale prospective multicenter clinical trial of early screening for cancer.<\/p>\n\n\n\n<p>On March 5, 2021, the official publication of &#8220;China Organ Review&#8221; stated that, &#8220;No prospective clinical trials have been conducted on the previously approved products in accordance with the above requirements. Only patients with different stages of colorectal cancer. And non-colorectal cancer patients were enrolled to evaluate the clinical sensitivity and specificity of the products. And the positive predictive value and negative predictive value of the products could not be systematically evaluated. 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