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style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<h2 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class=\"wp-block-image aligncenter size-large\"><img decoding=\"async\" src=\"http:\/\/cxounion.cn\/wp-content\/uploads\/2023\/06\/CXOUNION\u65b0\u4e8c\u7ef4\u7801.png\" alt=\"\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u7ffb\u8bd1\uff1a<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">In Wenzhou Lucheng District Li Yang Xin Road, it is difficult to imagine that there is still a hidden Haikang biological such a high-tech enterprise. <\/h2>\n\n\n\n<p>The appearance of the factory in the 1980s and 1990s is in stark contrast to the new residential buildings around it, which also makes this enterprise that has gone through wind and rain for nearly 30 years, more of the imprint of The Times.<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<p>From the small business of Wenzhou downtown blood station, to now gallop in the ranks of national high-tech enterprises, but also the only blood products production enterprise in the province. The rise of Haikang creatures is not so much the hero created by The Times as the breakout of active survival.<\/p>\n\n\n\n<p>From the breakthrough of raw materials to the breakthrough of system and mechanism, from the breakthrough of product research and development to the breakthrough of process improvement, under the leadership of Shen Rongjie, the &#8220;old blood station man&#8221;, Haikang Bio-prominent and sudden rise, relying on three single-collection plasma raw material bases, so that the blood products in Wenzhou and even the province from scratch, from there to excellent.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">In June 1996, according to the spirit of the relevant documents of the municipal government<\/h2>\n\n\n\n<p> Wenzhou Conch Industry Group Co., LTD. (now Wenzhou Conch Group Co., LTD., hereinafter referred to as &#8220;Conch Group&#8221;) . And Zhejiang Blood Products Institute jointly established Zhejiang Haikang Biological Products Co., LTD. Private enterprises hand in hand with state-owned institutions to open a long and difficult new journey.  But also for the development of blood products industry in our province into a new impetus.<\/p>\n\n\n\n<p>&#8220;From 1996 to 2006, this is the first 10 years of Haikang&#8217;s development, because it can also rely on the original resource development of Zhejiang blood products, from raw materials to talents have a certain guarantee, the enterprise can steadily advance and gradually grow.&#8221; However, in March 2006, after Zhejiang Blood Products Institute completed the restructuring of public institutions,<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<p> Haikang Biological became a wholly-owned subsidiary of Conch Group. Completely bid farewell to the comfort of the system.  Turned to the fierce market, we once fell into the trough of development.&#8221; Recalling the development process of the enterprise, in the view of Shen Rongjie.  The general manager of the company, the decade from 2006 to 2016 is a really difficult decade for Haikang Biology.<\/p>\n\n\n\n<p>According to Shen Rongjie, blood products are plasma protein products, such as human blood albumin, human immunoglobulin and human clotting factor, prepared by biotechnology such as separation, purification and virus inactivation, which are made from healthy human plasma or specific immune human plasma. It is mainly used for the treatment of severe patients such as burns, liver disease, blood loss and shock, and the diagnosis, treatment or passive immune prevention of diseases such as immune system deficiency, viral infection and coagulation dysfunction. Therefore, it is not too much to say that &#8220;blood products are life-saving drugs for ordinary people&#8221;.<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Plasma is the only raw material for the production of blood products by Hikon. <\/h2>\n\n\n\n<p>And the only source is donations from healthy people. &#8220;In 2006, Haikang biology was struggling and did not have its own raw material base in Zhejiang Province. At that time, I literally carried a briefcase to every corner of the province. I remember that in 2008, when I established the first raw plasma base of Haikang Biology in Panan County, Jinhua, I led the publicity team to communicate with villagers almost door-to-door to mobilize and motivate them to donate plasma. People in mountainous areas have good physical fitness and simple thinking, plus they will get certain economic subsidies for donating blood plasma, which is an additional income for people in mountainous areas, so our pulp extraction base will consider building in remote and poor mountainous areas.&#8221; Shen Rongjie said.<\/p>\n\n\n\n<p>Its own initiative and strong support from the provincial government, the Provincial Health Commission, the Wenzhou Municipal government and the Wenzhou Municipal Health Commission. Haikang Biological finally in this 10 years, from the original no bag of pulp, no raw material base, has built Panan, Wencheng, Qingtian three single collection of plasma raw material base. At present, Hikang biological plasma collection volume has reached more than 70 tons.  And the company has gradually stepped into the right track.<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Keep the security line intelligent digital guarantee quality<\/h2>\n\n\n\n<p>For Haikang biology, ensuring the safety of raw materials, production safety.  Product safety and other aspects of safety is a sword hanging on the hearts of each Haikang. And it is also the foundation of the enterprise.<\/p>\n\n\n\n<p>&#8220;Blood products are a special industry with very strict disinfection procedures for the production environment.&#8221; Shen Rongjie introduced. Through the monitoring screen outside the aseptic workshop, the reporter saw that the staff entered the first door to change into isolation clothing for strict disinfection, the workshops of different processes in the production workshop are independently separated, and after entering the workshop, it is also necessary to replace the sterile isolation clothing with more strict protection, and the number of people entering the production workshop also has strict requirements. From the multiple disinfection of raw materials to the separation and purification of extracts to the operation of product filling by machines on behalf of people.  Haikang&#8217;s rigorous quality control is reflected everywhere.<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">In October 2020, with the strong support of the Zhejiang Provincial Health Commission, <\/h2>\n\n\n\n<p>Haikang Biological undertook the construction of the Zhejiang Province plasma Collection Station management information system, which realized the interconnection of information between blood stations and plasma collection stations in Zhejiang Province. It has made due contributions to the standardization, standardization, specialization and refinement of the management of plasma collection station in our province.<\/p>\n\n\n\n<p>In January 2021, the Zhejiang Provincial Food . And Drug Administration issued an initiative on promoting the construction of the &#8220;black box&#8221; project of Zhejiang pharmaceutical chain. The &#8220;black box&#8221; project is an important measure to implement the national smart drug supervision and the digital reform of Zhejiang Provincial Party Committee and provincial government. Relying on the digital intelligent system of drug production enterprises, the drug regulatory department collects key parameters and data in the process of drug production and testing online and stores them in special media (namely &#8220;black box&#8221;), and uses the &#8220;black box&#8221; terminal data to conduct risk investigation and assessment. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<p>An important means to realize off-site intelligent supervision of drug production. Haikang Biological responded positively, took the lead in joining the &#8220;black box&#8221; project construction.  And was included in the pilot enterprise of the &#8220;black box&#8221; project construction in Wenzhou by the Provincial Food . And Drug Administration.  Becoming the first enterprise in Wenzhou to apply the &#8220;black box&#8221; of drugs.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">At present, Hikang Biological has automatically collected key parameters affecting drug quality such as material management,<\/h2>\n\n\n\n<p> production process, quality inspection, and product release collected from the production source of enterprises.  And achieved automatic collection of key data, intelligent verification of data content, and timely warning of risk signals. Through a box of tube data, two-way tube security, the whole process can be traced to further promote the transformation of enterprises to intelligent &#8220;digital factory&#8221; and &#8220;future factory&#8221;.<\/p>\n\n\n\n<p>&#8220;Now every bottle of our products produced by Hikang Biology from raw plasma collection to the whole process of production and clinical use of patients, to achieve the full traceability of key data information from &#8216;vaso-vascular&#8217;.&#8221; This information is automatically captured from the company&#8217;s key data information management system, &#8220;he said. Shen Rongjie stressed that since the company&#8217;s products were put on the market through the pharmaceutical GMP certification in 1998.  There have been no complaints about quality problems for more than 20 years. Now the company&#8217;s entire product quality tracking, each link, key data, can be automatically uploaded to the provincial drug &#8220;black box&#8221; regulatory system, which is the icing on the cake for the quality control of Haikang biology.&#8221;<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Permanent innovation to improve the process of new product development is not wrong<\/h2>\n\n\n\n<p>In December 2016, Hikang Biology ushered in a historic moment of the enterprise, the company completed the equity restructuring, and became a joint venture company of Tonglu Biopharmaceutical Co., LTD., a subsidiary of Shanghai Raishi Blood Products Co., LTD., and Wenzhou Conch Group Co., LTD. With the help of listed companies, Haikang Biology has entered the fast lane of new product research and development. Whether in terms of capital investment, process technology docking or public resource sharing, listed companies have provided strong support for Haikang Biological. As an old shareholder of Hikang Biology, Conch Group also strongly supports the technology research and development work of Hikang Biology.  And especially vacates an office building with an area of 300 square meters to use as the laboratory animal center of Hikang Biology to further empower the development of the enterprise.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The key to improve the competitiveness of enterprises depends on scientific and technological innovation,<\/h2>\n\n\n\n<p>Haikang biological attaches great importance to the research and development of new products.  And the annual research and development investment increases year by year. By increasing scientific and technological investment, improve the comprehensive utilization rate of raw material plasma. Improve and enhance the industrial structure.  And improve the core competitiveness of enterprises.<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-white-color\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/mark><\/p>\n\n\n\n<p> Haikang Biological currently has 15 patents, including 2 invention patents, 13 utility model patents and 1 software copyright. At present, the main products are: human blood albumin, intravenous injection of human immunoglobulin. Hepatitis B human immunoglobulin, intramuscular injection of human immunoglobulin, of which human blood albumin. Intravenous injection of human immunoglobulin are high-tech products in Zhejiang Province.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">As a special drug for the treatment of the novel coronavirus pneumonia, <\/h2>\n\n\n\n<p>intravenous human immunoglobulin has played an important role in the defense and fight against the novel coronavirus epidemic. And has been included in the supervision of important medical materials in Zhejiang Province. It is worth mentioning that Haikang Bio is also a key manufacturer of antiviral drugs for the prevention . And control of the novel coronavirus pneumonia epidemic. Since the outbreak of the epidemic, Hikang Bio and its parent companies (Shanghai Raishi, Tonglu Bio) have sent nearly 1 million bottles of human immunoglobulin and human blood albumin for intravenous injection to first-line hospitals in Wuhan, Hubei, Zhejiang, Guizhou, Chongqing, Jiangsu and other provinces, making contributions to the fight against the epidemic.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">In recent years, with the expansion of the production scale,<\/h2>\n\n\n\n<p> in addition to the production of human blood albumin and intravenous injection of human immunoglobulin, Haikang Biology also makes full use of the technological research and development advantages of Shanghai Laiss and Tonglu Biology.  And increases the product research and development of &#8220;tetanus human immunoglobulin&#8221; and &#8220;Rabies human immunoglobulin&#8221;. And create conditions to start the development of coagulation factor sub-products (human fibrinogen, human coagulation factor \u2167, human prothrombin complex, etc.), improve the core competitiveness of Haikang biology. For this reason, Hikang has set up a technology research and development team. Hoping to develop and put into clinical use in the next 3 to 5 years.<\/p>\n\n\n\n<p>It is reported that the construction of the new Haikang biological Park has also been planned, and the goal is to build a modern blood products production park with more than 300 tons of plasma, 12 varieties of three categories, an annual output of 3 million bottles (branches) of blood products, an annual output value of 800 million yuan, and a tax profit of more than 300 million yuan, making greater contributions to the biomedical industry in Zhejiang Province.<\/p>\n\n\n\n<p class=\"has-text-align-center has-cyan-bluish-gray-color has-text-color has-small-font-size\">\u672c\u6587\u7531<a href=\"http:\/\/cxounion.cn\">CXO UNION-CXO\u8054\u76df\uff08cxounion.cn\uff09<\/a>\u8f6c\u8f7d\u800c\u6210\uff0c\u6765\u6e90\u4e8e\u5065\u5eb7\u6e29\u5546\uff1b\u7f16\u8f91\/\u7ffb\u8bd1\uff1aCXO UNIONCXO\u8054\u76df\u5c0fU\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center 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